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DECLOMYCIN vs TETRACYCLINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. DECLOMYCIN and TETRACYCLINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

~$104.20 /30
~$17.90 /30

Type

RX
RX

Active ingredient

DEMECLOCYCLINE HYDROCHLORIDE
TETRACYCLINE HYDROCHLORIDE

Dosage forms

Tablet
Capsule, Tablet

Drug class

Tetracycline-Class Antimicrobial
Tetracycline-Class Antimicrobial

Boxed warning

None
None

Treats

Acne Vulgaris, Actinomycosis, Campylobacter Infections
Acne Vulgaris, Bartonella Infections, Borrelia Infections

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Frequently asked questions

Which is cheaper, Declomycin or Tetracycline Hydrochloride?

Tetracycline Hydrochloride costs pharmacies less to acquire — about $17.90 vs $104.20 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Declomycin and Tetracycline Hydrochloride?

Declomycin contains Demeclocycline Hydrochloride, while Tetracycline Hydrochloride contains Tetracycline Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.