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DAYPRO vs INDOCIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. DAYPRO and INDOCIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

60/100
70/100

Pharmacy pays

~$17.35 /30
~$4.06 /30

Type

RX
RX

Active ingredient

OXAPROZIN
INDOMETHACIN

Dosage forms

Tablet
Suppository

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None
None

Half-life

—
about 4.5 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Osteoarthritis
Rheumatoid Arthritis, Bursitis, Patent Ductus Arteriosus

Frequently asked questions

Which is better-rated, Daypro or Indocin?

By our independent rating, Indocin scores higher — 3.5 vs 3.0 out of 5 for Daypro. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Daypro or Indocin?

Indocin costs pharmacies less to acquire — about $4.06 vs $17.35 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Daypro and Indocin?

Daypro contains Oxaprozin, while Indocin contains Indomethacin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.