CORTONE vs HYDROCORTISONE VALERATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CORTONE and HYDROCORTISONE VALERATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CORTONE	HYDROCORTISONE VALERATE
Rating	70/100	62/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	CORTISONE ACETATE	HYDROCORTISONE VALERATE
Manufacturer	Merck	Glenmark Pharms Ltd
Dosage forms	Injectable, Tablet	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	about 1.5 hours
Treats	Adrenal Insufficiency, Asthma, Berylliosis	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

cortone hydrocortisone valerate

Rating

70/100

62/100

Pharmacy pays

—

Type

Active ingredient

CORTISONE ACETATE

HYDROCORTISONE VALERATE

Manufacturer

Merck

Glenmark Pharms Ltd

Dosage forms

Injectable, Tablet

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

about 1.5 hours

Treats

Adrenal Insufficiency, Asthma, Berylliosis

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Get hydrocortisone valerate

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Frequently asked questions

Which is better-rated, Cortone or Hydrocortisone Valerate?

By our independent rating, Cortone scores higher — 3.5 vs 3.1 out of 5 for Hydrocortisone Valerate. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cortone and Hydrocortisone Valerate?

Cortone contains Cortisone Acetate, while Hydrocortisone Valerate contains Hydrocortisone Valerate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.