COLAZAL vs ROXICET 5/500

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. COLAZAL and ROXICET 5/500 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	COLAZAL	ROXICET 5/500
Rating	74/100	70/100
Pharmacy pays	~$11.02 /30	$0.03 /mL
Type	RX	RX
Active ingredient	BALSALAZIDE DISODIUM	ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Roxane
Dosage forms	Capsule	Tablet
Drug class	Aminosalicylate	—
Boxed warning	None	None
Half-life	—	about 3.5 to 4 hours
Treats	Ulcerative Colitis	—

colazal roxicet 5/500

Rating

74/100

70/100

Pharmacy pays

~$11.02 /30

$0.03 /mL

Type

Active ingredient

BALSALAZIDE DISODIUM

ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Roxane

Dosage forms

Capsule

Tablet

Drug class

Aminosalicylate

—

Boxed warning

None

Half-life

—

about 3.5 to 4 hours

Treats

Ulcerative Colitis

—

Frequently asked questions

Which is better-rated, Colazal or Roxicet 5/500?

By our independent rating, Colazal scores higher — 3.7 vs 3.5 out of 5 for Roxicet 5/500. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Colazal and Roxicet 5/500?

Colazal contains Balsalazide Disodium, while Roxicet 5/500 contains Acetaminophen and Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.