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CHILDREN'S ALLEGRA ALLERGY vs ZYRTEC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 25, 2026·How we rate

Rating

New
New

Pharmacy pays

~$7.33 /30
$0.06 /mL

Type

RX
OTC

Active ingredient

FEXOFENADINE HYDROCHLORIDE
CETIRIZINE HYDROCHLORIDE

Manufacturer

Dosage forms

Tablet, orally disintegrating
Tablet, chewable

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Half-life

about 14 hours (label: mean elimination half-life 14.4 hours)
about 8.3 hours (mean in healthy adults)

Treats

Perennial Allergic Rhinitis, Urticaria
Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Children's Allegra Allergy and Zyrtec?

Children's Allegra Allergy contains Fexofenadine Hydrochloride, while Zyrtec contains Cetirizine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.