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CELECOXIB vs INDOMETHACIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. CELECOXIB and INDOMETHACIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

64/100
72/100

Pharmacy pays

~$2.51 /30
~$4.06 /30

Type

RX
RX

Active ingredient

CELECOXIB
INDOMETHACIN

Manufacturer

Dosage forms

Capsule
Capsule, Capsule, extended release, Suppository

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 11 hours
about 4.5 hours

Treats

Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis
Rheumatoid Arthritis, Bursitis, Patent Ductus Arteriosus

Frequently asked questions

Which is better-rated, Celecoxib or Indomethacin?

By our independent rating, Indomethacin scores higher — 3.6 vs 3.2 out of 5 for Celecoxib. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Celecoxib or Indomethacin?

Celecoxib costs pharmacies less to acquire — about $2.51 vs $4.06 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Celecoxib and Indomethacin?

Celecoxib contains Celecoxib, while Indomethacin contains Indomethacin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.