CEFOTAN vs TRIMETHOPRIM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. CEFOTAN and TRIMETHOPRIM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CEFOTAN	TRIMETHOPRIM
Rating	72/100	54/100
Pharmacy pays	—	~$35.33 /30
Type	RX	RX
Active ingredient	CEFOTETAN DISODIUM	TRIMETHOPRIM
Manufacturer	Pai Holdings Pharm	Teva
Dosage forms	Injectable	Tablet
Drug class	Cephalosporin Antibacterial	Dihydrofolate Reductase Inhibitor Antibacterial
Boxed warning	None	None
Half-life	—	about 8 to 10 hours
Treats	Abscess, Bacteroides Infections, Human Bites	Bronchitis, Escherichia Coli Infections, Klebsiella Infections

cefotan trimethoprim

Rating

72/100

54/100

Pharmacy pays

—

~$35.33 /30

Type

Active ingredient

CEFOTETAN DISODIUM

TRIMETHOPRIM

Manufacturer

Pai Holdings Pharm

Teva

Dosage forms

Injectable

Tablet

Drug class

Cephalosporin Antibacterial

Dihydrofolate Reductase Inhibitor Antibacterial

Boxed warning

None

Half-life

—

about 8 to 10 hours

Treats

Abscess, Bacteroides Infections, Human Bites

Bronchitis, Escherichia Coli Infections, Klebsiella Infections

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Frequently asked questions

Which is better-rated, Cefotan or Trimethoprim?

By our independent rating, Cefotan scores higher — 3.6 vs 2.7 out of 5 for Trimethoprim. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cefotan and Trimethoprim?

Cefotan contains Cefotetan Disodium, while Trimethoprim contains Trimethoprim — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.