BUTALBITAL, ASPIRIN AND CAFFEINE vs CUPRIMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. BUTALBITAL, ASPIRIN AND CAFFEINE and CUPRIMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BUTALBITAL, ASPIRIN AND CAFFEINE	CUPRIMINE
Rating	New	74/100
Pharmacy pays	~$0.78 /30	—
Type	RX	RX
Active ingredient	ASPIRIN AND BUTALBITAL AND CAFFEINE	PENICILLAMINE
Manufacturer	Quantum Pharmics	Valeant Pharm Intl
Dosage forms	Tablet	Capsule
Drug class	—	Antirheumatic Agent
Boxed warning	None	Boxed warning
Half-life	about 20 minutes (the label also states 0.33 hours) for aspirin itself	—
Treats	—	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

butalbital, aspirin and caffeine cuprimine

Rating

New

74/100

Pharmacy pays

~$0.78 /30

—

Type

Active ingredient

ASPIRIN AND BUTALBITAL AND CAFFEINE

PENICILLAMINE

Manufacturer

Quantum Pharmics

Valeant Pharm Intl

Dosage forms

Tablet

Capsule

Drug class

—

Antirheumatic Agent

Boxed warning

None

Boxed warning

Half-life

about 20 minutes (the label also states 0.33 hours) for aspirin itself

—

Treats

—

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

Frequently asked questions

What is the difference between Butalbital, Aspirin and Caffeine and Cuprimine?

Butalbital, Aspirin and Caffeine contains Aspirin and Butalbital and Caffeine, while Cuprimine contains Penicillamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.