BREZTRI AEROSPHERE vs RETIN-A

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. BREZTRI AEROSPHERE and RETIN-A are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BREZTRI AEROSPHERE	RETIN-A
Rating	New	74/100
Pharmacy pays	$0.75 /mL	$1.05 /g
Type	RX	RX
Active ingredient	BUDESONIDE AND FORMOTEROL FUMARATE AND GLYCOPYRROLATE	TRETINOIN
Manufacturer	Astrazeneca Ab	Valeant Pharm Intl
Dosage forms	Spray/Inhaler, metered	Topical
Drug class	—	Retinoid
Boxed warning	None	None
Half-life	about 2 to 3.6 hours (terminal elimination half-life, measured after intravenous dosing)	—
Treats	—	Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

breztri aerosphere retin-a

Rating

New

74/100

Pharmacy pays

$0.75 /mL

$1.05 /g

Type

Active ingredient

BUDESONIDE AND FORMOTEROL FUMARATE AND GLYCOPYRROLATE

TRETINOIN

Manufacturer

Astrazeneca Ab

Valeant Pharm Intl

Dosage forms

Spray/Inhaler, metered

Topical

Drug class

—

Retinoid

Boxed warning

None

Half-life

about 2 to 3.6 hours (terminal elimination half-life, measured after intravenous dosing)

—

Treats

—

Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

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Frequently asked questions

What is the difference between Breztri Aerosphere and Retin-A?

Breztri Aerosphere contains Budesonide and Formoterol Fumarate and Glycopyrrolate, while Retin-A contains Tretinoin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.