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BENYLIN vs DIPHENHYDRAMINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

$0.04 /mL
$0.04 /mL

Type

RX
RX

Active ingredient

DIPHENHYDRAMINE HYDROCHLORIDE
DIPHENHYDRAMINE HYDROCHLORIDE

Manufacturer

Dosage forms

Syrup, Solution
Injectable, Solution, Capsule, Tablet

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Treats

Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness
Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness

Get benylinhigher-rated option

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Frequently asked questions

Which is cheaper, Benylin or Diphenhydramine Hydrochloride?

Pharmacies pay about the same to acquire either one — roughly $0.04 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Benylin and Diphenhydramine Hydrochloride?

Both Benylin and Diphenhydramine Hydrochloride share the active ingredient Diphenhydramine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.