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BENADRYL vs CHLOR-TRIMETON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. BENADRYL and CHLOR-TRIMETON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

benadrylchlor-trimeton

Rating

New
New

Pharmacy pays

$0.04 /mL
—

Type

RX
RX

Active ingredient

DIPHENHYDRAMINE HYDROCHLORIDE
CHLORPHENIRAMINE MALEATE

Manufacturer

Mcneil Cons
Schering

Dosage forms

Tablet, Kit
Tablet, extended release, Injectable

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Treats

Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness
Perennial Allergic Rhinitis, Urticaria

Get benadrylhigher-rated option

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Frequently asked questions

What is the difference between Benadryl and Chlor-Trimeton?

Benadryl contains Diphenhydramine Hydrochloride, while Chlor-Trimeton contains Chlorpheniramine Maleate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.