BENADRYL PRESERVATIVE FREE vs TELDRIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. BENADRYL PRESERVATIVE FREE and TELDRIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BENADRYL PRESERVATIVE FREE	TELDRIN
Rating	New	70/100
Pharmacy pays	$0.04 /mL	—
Type	RX	RX
Active ingredient	DIPHENHYDRAMINE HYDROCHLORIDE	CHLORPHENIRAMINE MALEATE
Manufacturer	Mcneil Cons	Glaxosmithkline
Dosage forms	Injectable	Capsule, extended release
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Treats	Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness	Perennial Allergic Rhinitis, Urticaria

benadryl preservative free teldrin

Rating

New

70/100

Pharmacy pays

$0.04 /mL

—

Type

Active ingredient

DIPHENHYDRAMINE HYDROCHLORIDE

CHLORPHENIRAMINE MALEATE

Manufacturer

Mcneil Cons

Glaxosmithkline

Dosage forms

Injectable

Capsule, extended release

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Treats

Anxiety Disorders, Sleep Initiation and Maintenance Disorders, Motion Sickness

Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Benadryl Preservative Free and Teldrin?

Benadryl Preservative Free contains Diphenhydramine Hydrochloride, while Teldrin contains Chlorpheniramine Maleate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.