AVACLYR vs SITAVIG

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 30, 2026·How we rate

Attribute	AVACLYR	SITAVIG
Rating	New	New
Pharmacy pays	~$4.83 /30	~$4.83 /30
Type	RX	RX
Active ingredient	ACYCLOVIR	ACYCLOVIR
Manufacturer	Fera Pharms LLC	Ligand Pharms
Dosage forms	Topical	Tablet
Drug class	Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor	Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor
Boxed warning	None	None
Half-life	about 2.5 to 3.3 hours	about 2.5 to 3.3 hours
Treats	Chickenpox, Herpes Genitalis, Herpes Labialis	Chickenpox, Herpes Genitalis, Herpes Labialis

avaclyr sitavig

Rating

New

Pharmacy pays

~$4.83 /30

Type

Active ingredient

ACYCLOVIR

Manufacturer

Fera Pharms LLC

Ligand Pharms

Dosage forms

Topical

Tablet

Drug class

Herpes Simplex Virus Nucleoside Analog Dna Polymerase Inhibitor

Boxed warning

None

Half-life

about 2.5 to 3.3 hours

Treats

Chickenpox, Herpes Genitalis, Herpes Labialis

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Frequently asked questions

Which is cheaper, Avaclyr or Sitavig?

Pharmacies pay about the same to acquire either one — roughly $4.83 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Avaclyr and Sitavig?

Both Avaclyr and Sitavig share the active ingredient Acyclovir.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.