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ATROVENT HFA vs PERIACTIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ATROVENT HFA and PERIACTIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

$0.62 /mL
$0.07 /mL

Type

RX
RX

Active ingredient

IPRATROPIUM BROMIDE
CYPROHEPTADINE HYDROCHLORIDE

Dosage forms

Spray/Inhaler, metered
Syrup, Tablet

Drug class

Anticholinergic

Boxed warning

None
None

Treats

Bronchial Spasm, Bronchitis, Pulmonary Emphysema
Blepharospasm, Cluster Headache, Nelson Syndrome

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Frequently asked questions

Which is better-rated, Atrovent Hfa or Periactin?

By our independent rating, Atrovent Hfa scores higher — 3.6 vs 3.5 out of 5 for Periactin. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Atrovent Hfa or Periactin?

Periactin costs pharmacies less to acquire — about $0.07 vs $0.62 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Atrovent Hfa and Periactin?

Atrovent Hfa contains Ipratropium Bromide, while Periactin contains Cyproheptadine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.