ASENDIN vs PERTOFRANE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. ASENDIN and PERTOFRANE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ASENDIN	PERTOFRANE
Rating	New	70/100
Pharmacy pays	—	~$8.39 /30
Type	RX	RX
Active ingredient	AMOXAPINE	DESIPRAMINE HYDROCHLORIDE
Manufacturer	Lederle	Sanofi Aventis US
Dosage forms	Tablet	Capsule
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	None	None
Treats	Depressive Disorder, Psychophysiologic Disorders	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Pain

asendin pertofrane

Rating

New

70/100

Pharmacy pays

—

~$8.39 /30

Type

Active ingredient

AMOXAPINE

DESIPRAMINE HYDROCHLORIDE

Manufacturer

Lederle

Sanofi Aventis US

Dosage forms

Tablet

Capsule

Drug class

Tricyclic Antidepressant

Boxed warning

None

Treats

Depressive Disorder, Psychophysiologic Disorders

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Pain

Get pertofranehigher-rated option

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Frequently asked questions

What is the difference between Asendin and Pertofrane?

Asendin contains Amoxapine, while Pertofrane contains Desipramine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.