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ASENAPINE MALEATE vs SAPHRIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Rating

70/100
70/100

Pharmacy pays

~$73.98 /30
~$73.98 /30

Type

RX
RX

Active ingredient

ASENAPINE MALEATE
ASENAPINE MALEATE

Manufacturer

Dosage forms

Tablet
Tablet

Drug class

Atypical Antipsychotic
Atypical Antipsychotic

Half-life

about 24 hours (terminal/elimination half-life)
about 24 hours (terminal/elimination half-life)

Treats

Bipolar Disorder, Schizophrenia
Bipolar Disorder, Schizophrenia

Frequently asked questions

Which is better-rated, Asenapine Maleate or Saphris?

Asenapine Maleate and Saphris are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Asenapine Maleate or Saphris?

Pharmacies pay about the same to acquire either one — roughly $73.98 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Asenapine Maleate and Saphris?

Both Asenapine Maleate and Saphris share the active ingredient Asenapine Maleate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.