ALPRAZOLAM vs SYMPAZAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ALPRAZOLAM and SYMPAZAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALPRAZOLAM	SYMPAZAN
Rating	66/100	New
Pharmacy pays	~$0.76 /30	~$7.72 /30
Type	RX	RX
Active ingredient	ALPRAZOLAM	CLOBAZAM
Manufacturer	Apotex	Assertio Speclty
Dosage forms	Solution, Tablet, Tablet, extended release, Tablet, orally disintegrating	Film
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	None	Boxed warning
Half-life	about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults	—
Treats	Agoraphobia, Depressive Disorder, Panic Disorder	Seizures, Lennox Gastaut Syndrome

alprazolam sympazan

Rating

66/100

New

Pharmacy pays

~$0.76 /30

~$7.72 /30

Type

Active ingredient

ALPRAZOLAM

CLOBAZAM

Manufacturer

Apotex

Assertio Speclty

Dosage forms

Solution, Tablet, Tablet, extended release, Tablet, orally disintegrating

Film

Drug class

Benzodiazepine

Boxed warning

None

Boxed warning

Half-life

about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults

—

Treats

Agoraphobia, Depressive Disorder, Panic Disorder

Seizures, Lennox Gastaut Syndrome

Frequently asked questions

Which is cheaper, Alprazolam or Sympazan?

Alprazolam costs pharmacies less to acquire — about $0.76 vs $7.72 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Alprazolam and Sympazan?

Alprazolam contains Alprazolam, while Sympazan contains Clobazam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.