ALPRAZOLAM vs KLONOPIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. ALPRAZOLAM and KLONOPIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALPRAZOLAM	KLONOPIN
Rating	66/100	New
Pharmacy pays	~$0.76 /30	~$0.83 /30
Type	RX	RX
Active ingredient	ALPRAZOLAM	CLONAZEPAM
Manufacturer	Apotex	Cheplapharm
Dosage forms	Solution, Tablet, Tablet, extended release, Tablet, orally disintegrating	Tablet
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	None	Boxed warning
Half-life	about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults	about 30 to 40 hours
Treats	Agoraphobia, Depressive Disorder, Panic Disorder	Bipolar Disorder, Dysarthria, Myoclonic Epilepsies

alprazolam klonopin

Rating

66/100

New

Pharmacy pays

~$0.76 /30

~$0.83 /30

Type

Active ingredient

ALPRAZOLAM

CLONAZEPAM

Manufacturer

Apotex

Cheplapharm

Dosage forms

Solution, Tablet, Tablet, extended release, Tablet, orally disintegrating

Tablet

Drug class

Benzodiazepine

Boxed warning

None

Boxed warning

Half-life

about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults

about 30 to 40 hours

Treats

Agoraphobia, Depressive Disorder, Panic Disorder

Bipolar Disorder, Dysarthria, Myoclonic Epilepsies

Frequently asked questions

Which is cheaper, Alprazolam or Klonopin?

Alprazolam costs pharmacies less to acquire — about $0.76 vs $0.83 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Alprazolam and Klonopin?

Alprazolam contains Alprazolam, while Klonopin contains Clonazepam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.