ALEVE vs NAPRELAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	ALEVE	NAPRELAN
Rating	New	New
Pharmacy pays	$0.06 /mL	$0.06 /mL
Type	OTC	RX
Active ingredient	NAPROXEN SODIUM	NAPROXEN SODIUM
Manufacturer	Bayer Pharms	Twi Pharms
Dosage forms	Capsule, Tablet	Tablet, extended release
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	Boxed warning
Half-life	about 12 to 17 hours	about 12 to 17 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Back Pain	Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

aleve naprelan

Rating

New

Pharmacy pays

$0.06 /mL

Type

OTC

Active ingredient

NAPROXEN SODIUM

Manufacturer

Bayer Pharms

Twi Pharms

Dosage forms

Capsule, Tablet

Tablet, extended release

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Boxed warning

Half-life

about 12 to 17 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

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Where to buy

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Frequently asked questions

Which is cheaper, Aleve or Naprelan?

Pharmacies pay about the same to acquire either one — roughly $0.06 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Aleve and Naprelan?

Both Aleve and Naprelan share the active ingredient Naproxen Sodium, but Aleve is sold as OTC and Naprelan as RX.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.