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AFINITOR vs ZORTRESS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

70/100
70/100

Pharmacy pays

~$229.16 /30
~$229.16 /30

Type

RX
RX

Active ingredient

EVEROLIMUS
EVEROLIMUS

Manufacturer

Dosage forms

Tablet
Tablet

Drug class

Kinase Inhibitor
Kinase Inhibitor

Boxed warning

Half-life

about 30 hours (mean terminal elimination half-life)
about 30 hours (mean terminal elimination half-life)

Frequently asked questions

Which is better-rated, Afinitor or Zortress?

Afinitor and Zortress are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Afinitor or Zortress?

Pharmacies pay about the same to acquire either one — roughly $229.16 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Afinitor and Zortress?

Both Afinitor and Zortress share the active ingredient Everolimus.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.