ACULAR vs PROTAMINE SULFATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. ACULAR and PROTAMINE SULFATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	PROTAMINE SULFATE
Rating	72/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	PROTAMINE SULFATE
Manufacturer	Abbvie	Quad Pharms
Dosage forms	Drops	Injectable
Drug class	Nonsteroidal Anti-Inflammatory Drug	Heparin Reversal Agent
Boxed warning	None	None
Half-life	about 5 to 6 hours	—
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular protamine sulfate

Rating

72/100

New

Pharmacy pays

—

Type

Active ingredient

KETOROLAC TROMETHAMINE

PROTAMINE SULFATE

Manufacturer

Abbvie

Quad Pharms

Dosage forms

Drops

Injectable

Drug class

Nonsteroidal Anti-Inflammatory Drug

Heparin Reversal Agent

Boxed warning

None

Half-life

about 5 to 6 hours

—

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

What is the difference between Acular and Protamine Sulfate?

Acular contains Ketorolac Tromethamine, while Protamine Sulfate contains Protamine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.