ACULAR vs BUTALBITAL, ASPIRIN AND CAFFEINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACULAR and BUTALBITAL, ASPIRIN AND CAFFEINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR	BUTALBITAL, ASPIRIN AND CAFFEINE
Rating	72/100	New
Pharmacy pays	—	~$0.78 /30
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	ASPIRIN AND BUTALBITAL AND CAFFEINE
Manufacturer	Abbvie	Quantum Pharmics
Dosage forms	Drops	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	about 20 minutes (the label also states 0.33 hours) for aspirin itself
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular butalbital, aspirin and caffeine

Rating

72/100

New

Pharmacy pays

—

~$0.78 /30

Type

Active ingredient

KETOROLAC TROMETHAMINE

ASPIRIN AND BUTALBITAL AND CAFFEINE

Manufacturer

Abbvie

Quantum Pharmics

Dosage forms

Drops

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

about 20 minutes (the label also states 0.33 hours) for aspirin itself

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

What is the difference between Acular and Butalbital, Aspirin and Caffeine?

Acular contains Ketorolac Tromethamine, while Butalbital, Aspirin and Caffeine contains Aspirin and Butalbital and Caffeine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.