ACULAR LS vs ROXICET 5/500

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACULAR LS and ROXICET 5/500 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACULAR LS	ROXICET 5/500
Rating	72/100	New
Pharmacy pays	—	$0.03 /mL
Type	RX	RX
Active ingredient	KETOROLAC TROMETHAMINE	ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE
Manufacturer	Abbvie	Roxane
Dosage forms	Drops	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	—
Boxed warning	None	None
Half-life	about 5 to 6 hours	about 3.5 to 4 hours
Treats	Allergic Conjunctivitis, Inflammation, Pain	—

acular ls roxicet 5/500

Rating

72/100

New

Pharmacy pays

—

$0.03 /mL

Type

Active ingredient

KETOROLAC TROMETHAMINE

ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE

Manufacturer

Abbvie

Roxane

Dosage forms

Drops

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

—

Boxed warning

None

Half-life

about 5 to 6 hours

about 3.5 to 4 hours

Treats

Allergic Conjunctivitis, Inflammation, Pain

—

Frequently asked questions

What is the difference between Acular Ls and Roxicet 5/500?

Acular Ls contains Ketorolac Tromethamine, while Roxicet 5/500 contains Acetaminophen and Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.