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ACTONEL WITH CALCIUM (COPACKAGED) vs COLAZAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. ACTONEL WITH CALCIUM (COPACKAGED) and COLAZAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
74/100

Pharmacy pays

~$0.24 /30
~$11.02 /30

Type

RX
RX

Active ingredient

CALCIUM CARBONATE AND RISEDRONATE SODIUM
BALSALAZIDE DISODIUM

Dosage forms

Tablet
Capsule

Drug class

—
Aminosalicylate

Boxed warning

None
None

Half-life

about 561 hours — roughly 23 days
—

Treats

—
Ulcerative Colitis

Frequently asked questions

Which is better-rated, Actonel with Calcium (Copackaged) or Colazal?

By our independent rating, Colazal scores higher — 3.7 vs 3.6 out of 5 for Actonel with Calcium (Copackaged). Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Actonel with Calcium (Copackaged) or Colazal?

Actonel with Calcium (Copackaged) costs pharmacies less to acquire — about $0.24 vs $11.02 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Actonel with Calcium (Copackaged) and Colazal?

Actonel with Calcium (Copackaged) contains Calcium Carbonate and Risedronate Sodium, while Colazal contains Balsalazide Disodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.