actonel with calcium (copackaged)

How long does Calcium Carbonate and Risedronate Sodium stay in your body?

The elimination half-life of calcium carbonate and risedronate sodium is about 561 hours — roughly 23 days — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal (elimination) exponential half-life, the only half-life the label reports, measured in osteopenic postmenopausal women. It is very long because risedronate is slowly released back out of bone, where about 60% of an absorbed dose goes — it does not mean the drug stays in the blood for weeks; the label notes roughly half of the absorbed dose is excreted in the urine within 24 hours. There is no active metabolite and this is not a prodrug: the label states there is no evidence of systemic metabolism, and the drug is excreted unchanged. Populations the label names: older adults (over 60) — bioavailability and disposition are similar to younger subjects, no dosage adjustment. Kidney impairment — risedronate is cleared unchanged by the kidney, and renal clearance falls about 70% at a creatinine clearance around 30 mL/min; the label does not recommend it below 30 mL/min, but no adjustment is needed at 30 mL/min or above. Liver impairment — not studied, but risedronate is not metabolized by the liver, so the label says an adjustment is unlikely to be needed.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: ACTONEL (risedronate sodium) tablets — FDA label, DailyMed.

Frequently asked questions

How is Actonel with Calcium (Copackaged) rated?

pharmaranks gives Actonel with Calcium (Copackaged) a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Actonel with Calcium (Copackaged) cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.24 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Actonel with Calcium (Copackaged)?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Actonel with Calcium (Copackaged). To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Actonel with Calcium (Copackaged)?

Actonel with Calcium (Copackaged) is marketed by Warner Chilcott. You can see Warner Chilcott's full profile, rating, and other products on pharmaranks.

Is Actonel with Calcium (Copackaged) a brand-name or generic drug?

Actonel with Calcium (Copackaged) is a brand-name product with the active ingredient Calcium Carbonate and Risedronate Sodium.

Is Actonel with Calcium (Copackaged) available over the counter?

No. Actonel with Calcium (Copackaged) is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Actonel with Calcium (Copackaged) come in?

Actonel with Calcium (Copackaged) is currently marketed as tablet, per the FDA's National Drug Code Directory.

Is Actonel with Calcium (Copackaged) FDA-registered?

Actonel with Calcium (Copackaged) is on record with the U.S. FDA under application number NDA021823. You can verify this on its official FDA label.

Has Actonel with Calcium (Copackaged) been recalled by the FDA?

Actonel with Calcium (Copackaged) has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Actonel with Calcium (Copackaged) safe?

There's no single safe-or-not verdict. pharmaranks gives Actonel with Calcium (Copackaged) a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.