ACTIMMUNE vs KEYTRUDA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. ACTIMMUNE and KEYTRUDA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACTIMMUNE	KEYTRUDA
Rating	New	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	INTERFERON GAMMA-1B	PEMBROLIZUMAB
Manufacturer	Horizon Therapeutics Ireland Dac	Merck Sharp Dohme
Dosage forms	Injectable	Injectable
Drug class	Interferon Gamma	Programmed Death Receptor-1 Blocking Antibody
Boxed warning	None	None
Treats	Bacterial Infections, Brain Neoplasms, Renal Cell Carcinoma	Malignant Mesothelioma, Biliary Tract Neoplasms, Urinary Bladder Neoplasms

actimmune keytruda

Rating

New

70/100

Pharmacy pays

—

Type

Active ingredient

INTERFERON GAMMA-1B

PEMBROLIZUMAB

Manufacturer

Horizon Therapeutics Ireland Dac

Merck Sharp Dohme

Dosage forms

Injectable

Drug class

Interferon Gamma

Programmed Death Receptor-1 Blocking Antibody

Boxed warning

None

Treats

Bacterial Infections, Brain Neoplasms, Renal Cell Carcinoma

Malignant Mesothelioma, Biliary Tract Neoplasms, Urinary Bladder Neoplasms

Frequently asked questions

What is the difference between Actimmune and Keytruda?

Actimmune contains Interferon Gamma-1b, while Keytruda contains Pembrolizumab — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.