ACIPHEX vs PRILOSEC OTC
Independent side-by-side comparison.
Rating
New
70/100
Pharmacy pays
—
—
Type
RX
OTC
Active ingredient
RABEPRAZOLE SODIUM
OMEPRAZOLE MAGNESIUM
Manufacturer
Dosage forms
Tablet, delayed release
Tablet, delayed release
Drug class
Proton Pump Inhibitor
Proton Pump Inhibitor
Boxed warning
None
None
Half-life
—
about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults
Treats
Duodenal Ulcer, Gastroesophageal Reflux, Heartburn
Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux
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Where to buy
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Frequently asked questions
What is the difference between Aciphex and Prilosec OTC?
Aciphex contains Rabeprazole Sodium, while Prilosec OTC contains Omeprazole Magnesium — they have different active ingredients.
Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.