ABREVA vs ALEVE PM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	ABREVA	ALEVE PM
Rating	72/100	New
Pharmacy pays	$6.64 /g	$0.04 /mL
Type	OTC	OTC
Active ingredient	DOCOSANOL	DIPHENHYDRAMINE HYDROCHLORIDE AND NAPROXEN SODIUM
Manufacturer	Haleon US Holdings	Bayer Hlthcare
Dosage forms	Topical	Tablet
Drug class	—	—
Boxed warning	None	None
Half-life	—	about 12 to 17 hours
Treats	Blister	—

abreva aleve pm

Rating

72/100

New

Pharmacy pays

$6.64 /g

$0.04 /mL

Type

OTC

Active ingredient

DOCOSANOL

DIPHENHYDRAMINE HYDROCHLORIDE AND NAPROXEN SODIUM

Manufacturer

Haleon US Holdings

Bayer Hlthcare

Dosage forms

Topical

Tablet

Drug class

—

Boxed warning

None

Half-life

—

about 12 to 17 hours

Treats

Blister

—

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Frequently asked questions

What is the difference between Abreva and Aleve Pm?

Abreva contains Docosanol, while Aleve Pm contains Diphenhydramine Hydrochloride and Naproxen Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.