8-HOUR BAYER vs INDOMETHACIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. 8-HOUR BAYER and INDOMETHACIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	8-HOUR BAYER	INDOMETHACIN
Rating	New	72/100
Pharmacy pays	~$0.78 /30	~$4.06 /30
Type	RX	RX
Active ingredient	ASPIRIN	INDOMETHACIN
Manufacturer	Bayer Pharms	Rising
Dosage forms	Tablet, extended release	Capsule, Capsule, extended release, Suppository
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	about 20 minutes (the label also states 0.33 hours) for aspirin itself	about 4.5 hours
Treats	Rheumatoid Arthritis, Fever, Gout	Rheumatoid Arthritis, Bursitis, Patent Ductus Arteriosus

8-hour bayer indomethacin

Rating

New

72/100

Pharmacy pays

~$0.78 /30

~$4.06 /30

Type

Active ingredient

ASPIRIN

INDOMETHACIN

Manufacturer

Bayer Pharms

Rising

Dosage forms

Tablet, extended release

Capsule, Capsule, extended release, Suppository

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 20 minutes (the label also states 0.33 hours) for aspirin itself

about 4.5 hours

Treats

Rheumatoid Arthritis, Fever, Gout

Rheumatoid Arthritis, Bursitis, Patent Ductus Arteriosus

Frequently asked questions

Which is cheaper, 8-Hour Bayer or Indomethacin?

8-Hour Bayer costs pharmacies less to acquire — about $0.78 vs $4.06 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between 8-Hour Bayer and Indomethacin?

8-Hour Bayer contains Aspirin, while Indomethacin contains Indomethacin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.