Folate Analog Metabolic Inhibitor drugs compared
Compare all 7 Folate Analog Metabolic Inhibitor drugs side by side, used for conditions such as arthritis, juvenile, arthritis, rheumatoid, breast neoplasms. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is xatmep.
Top-rated folate analog metabolic inhibitor: 1. Xatmep · 2. Methotrexate Lpf · 3. Methotrexate Preservative Free
| Drug | Generic | Form | Status | Used for | Safety ratingFDA recall-based | Pharmacy pays |
|---|---|---|---|---|---|---|
| Xatmep | Methotrexate Sodium | Solution | Prescription | Arthritis, Juvenile, Arthritis, Rheumatoid | 70/100 | $5 |
| Methotrexate Lpf | Methotrexate Sodium | Injectable | Prescription | Arthritis, Juvenile, Arthritis, Rheumatoid | 54/100 | $5 |
| Methotrexate Preservative Free | Methotrexate Sodium | Injectable | Prescription | Arthritis, Juvenile, Arthritis, Rheumatoid | 54/100 | $5 |
| Alimta | Pemetrexed Disodium | Injectable | Prescription | Carcinoma, Non-Small-Cell Lung, Neoplasms, Mesothelial | Not yet rated | — |
| Folotyn | Pralatrexate | Injectable | Prescription | Lymphoma, T-Cell, Peripheral | Not yet rated | — |
| Jylamvo | Methotrexate | Solution | Prescription | Arthritis, Juvenile, Arthritis, Rheumatoid | Not yet rated | $5 |
| Rasuvo | Methotrexate | Injectable | Prescription | Arthritis, Juvenile, Arthritis, Rheumatoid | Not yet rated | $5 |
The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.
Best folate analog metabolic inhibitor by condition
Full ranking · 7 drugs
- 170/100
xatmep
Methotrexate Sodium
- 254/100
methotrexate lpf
Methotrexate Sodium
- 354/100
methotrexate preservative free
Methotrexate Sodium
- 4New
alimta
Pemetrexed Disodium
- 5New
folotyn
Pralatrexate
- 6New
jylamvo
Methotrexate
- 7New
rasuvo
Methotrexate
Frequently asked questions
What is the Folate Analog Metabolic Inhibitor drug class?
Folate Analog Metabolic Inhibitor is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 7 Folate Analog Metabolic Inhibitor products, each independently rated.
Are all Folate Analog Metabolic Inhibitor drugs the same?
No. Folate Analog Metabolic Inhibitor drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.
What conditions do Folate Analog Metabolic Inhibitor drugs treat?
Per NIH RxClass drug-classification data, Folate Analog Metabolic Inhibitor drugs are used for conditions including arthritis, juvenile, arthritis, rheumatoid, breast neoplasms, choriocarcinoma, crohn disease, esophageal neoplasms.
Which Folate Analog Metabolic Inhibitor drug is best-rated?
By our independent rating, xatmep currently ranks highest among Folate Analog Metabolic Inhibitor drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.
Sources: the Folate Analog Metabolic Inhibitor class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Methotrexate - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.