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Bile Acid Sequestrant drugs compared

Compare all 5 Bile Acid Sequestrant drugs side by side, used for conditions such as coronary artery disease, diarrhea, enterocolitis, pseudomembranous. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is cholestyramine.

Top-rated bile acid sequestrant: 1. Cholestyramine · 2. Colestipol Hydrochloride · 3. Colestid

Bile Acid Sequestrant drugs compared side by side, with pharmaranks' FDA recall-safety rating
DrugGenericSafety ratingFDA recall-based
Cholestyramine—70/100
Colestipol Hydrochloride—66/100
ColestidColestipol Hydrochloride64/100
Flavored ColestidColestipol Hydrochloride64/100
Colesevelam Hydrochloride—62/100

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Best bile acid sequestrant by condition

for coronary artery diseasefor diarrheafor pseudomembranous enterocolitisfor hypercholesterolemiafor hyperlipoproteinemiasfor hypertriglyceridemia

Full ranking · 5 drugs

  1. 1

    cholestyramine

    Cholestyramine

    70/100
  2. 2

    colestipol hydrochloride

    Colestipol Hydrochloride

    66/100
  3. 3

    colestid

    Colestipol Hydrochloride

    64/100
  4. 4

    flavored colestid

    Colestipol Hydrochloride

    64/100
  5. 5

    colesevelam hydrochloride

    Colesevelam Hydrochloride

    62/100

Frequently asked questions

What is the Bile Acid Sequestrant drug class?

Bile Acid Sequestrant is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 5 Bile Acid Sequestrant products, each independently rated.

Are all Bile Acid Sequestrant drugs the same?

No. Bile Acid Sequestrant drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

What conditions do Bile Acid Sequestrant drugs treat?

Per NIH RxClass drug-classification data, Bile Acid Sequestrant drugs are used for conditions including coronary artery disease, diarrhea, enterocolitis, pseudomembranous, hypercholesterolemia, hyperlipoproteinemias, hypertriglyceridemia.

Which Bile Acid Sequestrant drug is best-rated?

By our independent rating, cholestyramine currently ranks highest among Bile Acid Sequestrant drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Bile Acid Sequestrant class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class). Ratings are pharmaranks’ independent FDA recall-safety analysis.