What is the best bile acid sequestrant for hyperlipoproteinemias?

By our independent recall-safety rating — not an efficacy measure — colestipol hydrochloride ranks highest among Bile Acid Sequestrant drugs used for hyperlipoproteinemias. Always consult a professional.

Which bile acid sequestrant drugs treat hyperlipoproteinemias?

pharmaranks lists 4 Bile Acid Sequestrant products used for hyperlipoproteinemias, per NIH RxClass drug-classification data — each independently rated and ranked above.

How are these ranked?

By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.

Best Bile Acid Sequestrant for hyperlipoproteinemias

Top-rated pick: Colestipol Hydrochloride — pharmaranks score 66/100, the highest of the 4 Bile Acid Sequestrant drugs used for hyperlipoproteinemias, ranked by our independent FDA recall-safety score. Compare them with all treatments for hyperlipoproteinemias or the full Bile Acid Sequestrant class. Not medical advice — always consult a professional.

Quick answer: Of the 4 bile acid sequestrant drugs we rate for hyperlipoproteinemias, all are available as lower-cost generics, and most are suspension. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for hyperlipoproteinemias; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Other drug classes for hyperlipoproteinemias

Best hmg-coa reductase inhibitor Best peroxisome proliferator receptor alpha agonist

Top bile acid sequestrant for hyperlipoproteinemias: 1. Colestipol Hydrochloride · 2. Colestid · 3. Flavored Colestid

Best-rated Bile Acid Sequestrant for hyperlipoproteinemias, ranked by pharmaranks score
#	Drug	Rating	Type	Form	Generic?	Pharmacy pays
1	Colestipol Hydrochloride	66/100	Prescription	Suspension	Generic	$20	View →
2	Colestid	64/100	Prescription	Suspension	Generic	$20	View →
3	Flavored Colestid	64/100	Prescription	Suspension	Generic	$20	View →
4	Colesevelam Hydrochloride	62/100	Prescription	Suspension	Generic	$8	View →

Full ranking · 4 drugs

#3 of 7 in Bile Acid Sequestrant

colestipol hydrochloride

PrescriptionFDA-sourced

66/100

Colestipol Hydrochloride is a bile acid sequestrant used to treat Coronary Artery Disease, Diarrhea, Pseudomembranous Enterocolitis, Hypercholesterolemia.

(44 data points)

bile acid sequestrantcoronary artery diseasediarrhea

Pharmacy pays

~$20.09 /30

Save up to 58% in class

View details →

colestid

PrescriptionFDA-sourced

64/100

Colestid (Colestipol Hydrochloride) is a bile acid sequestrant used to treat Coronary Artery Disease, Diarrhea, Pseudomembranous Enterocolitis, Hypercholesterolemia.

(61 data points)

bile acid sequestrantcoronary artery diseasediarrhea

Pharmacy pays

~$20.09 /30

Save up to 58% in class

View details →

flavored colestid

PrescriptionFDA-sourced

64/100

Flavored Colestid (Colestipol Hydrochloride) is a bile acid sequestrant used to treat Coronary Artery Disease, Diarrhea, Pseudomembranous Enterocolitis, Hypercholesterolemia.

(61 data points)

bile acid sequestrantcoronary artery diseasediarrhea

Pharmacy pays

~$20.09 /30

Save up to 58% in class

View details →

colesevelam hydrochloride

PrescriptionFDA-sourced

62/100

Colesevelam Hydrochloride is a bile acid sequestrant used to treat Coronary Artery Disease, Type 2 Diabetes Mellitus, Diarrhea, Pseudomembranous Enterocolitis.

(67 data points)

bile acid sequestrantcoronary artery diseasediabetes mellitus, type 2

Pharmacy pays

From ~$8.11/30· 2 forms

View details →

Frequently asked

What is the best bile acid sequestrant for hyperlipoproteinemias?: By our independent recall-safety rating — not an efficacy measure — colestipol hydrochloride ranks highest among Bile Acid Sequestrant drugs used for hyperlipoproteinemias. Always consult a professional.
Which bile acid sequestrant drugs treat hyperlipoproteinemias?: pharmaranks lists 4 Bile Acid Sequestrant products used for hyperlipoproteinemias, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?: By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.