4 Proton Pump Inhibitor drugs indicated for heartburn, ranked by our independent rating. The current highest-rated is pantoprazole sodium. Compare them with all treatments for heartburn or the full Proton Pump Inhibitor class. Not medical advice — always consult a professional.
Top proton pump inhibitor for heartburn: 1. Pantoprazole Sodium · 2. Aciphex · 3. Dexilant
| # | Drug | Rating | Type | Typical price | |
|---|---|---|---|---|---|
| 1 | Pantoprazole Sodium | Not yet rated | Prescription | $121 | View → |
| 2 | Aciphex | Not yet rated | Prescription | — | View → |
| 3 | Dexilant | Not yet rated | Prescription | $128 |
Full ranking · 4 drugs
PrescriptionFDA-sourced
The active ingredient in Pantoprazole Sodium for Injection, a PPI, is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl] sulfinyl]-1 H -benzimidazole, a compound that inhibits gastric acid secretion.
Typical price
From ~$71.22/30· 2 forms Save up to 96% in class| View → |
| 4 | Prilosec OTC | Not yet rated | Over-the-counter | — | View → |
PrescriptionFDA-sourced
The active ingredient in rabeprazole sodium delayed-release tablets is rabeprazole sodium hydrate, USP, which is a proton pump inhibitor.
Price varies