Best Opioid Antagonist for constipation
2 Opioid Antagonist drugs used for constipation, ranked by our independent rating. Compare them with all treatments for constipation or the full Opioid Antagonist class. Not medical advice — always consult a professional.
Quick answer: Of the 2 opioid antagonist drugs we rate for constipation, none are yet flagged as generics in our price data, and most are injectable. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for constipation; the right choice depends on your situation, so confirm it with your prescriber.
How opioid antagonist work
Opioid antagonists attach to the same brain and body receptors that opioids use, but without switching them on. By occupying those receptors, they block opioids from binding and can rapidly reverse an overdose or curb opioid cravings.
Top opioid antagonist for constipation: 1. Relistor · 2. Symproic
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 2 | Not yet rated | Prescription | Tablet | No data | — | View → |
Full ranking · 2 drugs
relistor
PrescriptionFDA-sourced
Relistor (Methylnaltrexone Bromide) is an opioid antagonist used to treat Constipation.
Price varies
symproic
PrescriptionFDA-sourced
Symproic (Naldemedine Tosylate) is an opioid antagonist used to treat Constipation.
Price varies
Frequently asked
- What is the best opioid antagonist for constipation?
- Ratings are based on FDA regulatory recall-safety data — always consult a professional.
- Which opioid antagonist drugs treat constipation?
- pharmaranks lists 2 Opioid Antagonist products used for constipation, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.