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Best Angiotensin 2 Receptor Blocker for hypertension

Top-rated pick: Micardis — pharmaranks score 72/100, the highest of the 8 Angiotensin 2 Receptor Blocker drugs used for hypertension, ranked by our independent FDA recall-safety score. Compare them with all treatments for hypertension or the full Angiotensin 2 Receptor Blocker class. Not medical advice — always consult a professional.

Quick answer: Of the 8 angiotensin 2 receptor blocker drugs we rate for hypertension, all are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for hypertension; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

How angiotensin 2 receptor blocker work

Angiotensin II receptor blockers (ARBs) block the AT1 receptor that the hormone angiotensin II uses to tighten blood vessels and make the body hold onto salt and water. With that receptor blocked, vessels relax and widen, so blood pressure falls.

Source: Angiotensin II Receptor Blockers (ARB) - StatPearls - NCBI Bookshelf

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Top angiotensin 2 receptor blocker for hypertension: 1. Micardis · 2. Atacand · 3. Avapro

Best-rated Angiotensin 2 Receptor Blocker for hypertension, ranked by pharmaranks score
#DrugRatingPharmacy pays
172/100$5View →
270/100$16View →
370/100$3View →
470/100$2View →
570/100$4View →
666/100$3View →
7Not yet rated$1View →
8Not yet rated$5View →

Full ranking · 8 drugs

#1 of 8 in Angiotensin 2 Receptor Blocker

micardis

PrescriptionFDA-sourced

72/100

Micardis (Telmisartan) is an angiotensin 2 receptor blocker used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Left Ventricular Dysfunction.

(6 data points)
angiotensin 2 receptor blockerdiabetic nephropathiesheart failure

Pharmacy pays

From ~$3.15/30· 3 forms Save up to 78% in class
View details →
#2 of 8 in Angiotensin 2 Receptor Blocker

atacand

Boxed warning

PrescriptionFDA-sourced

70/100

Atacand (Candesartan Cilexetil) is an angiotensin 2 receptor blocker used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Left Ventricular Dysfunction.

(4 data points)
angiotensin 2 receptor blockerdiabetic nephropathiesheart failure

Pharmacy pays

From ~$14.66/30· 4 forms Save up to 94% in class
View details →
SANOFI AVENTIS US logo
#2 of 8 in Angiotensin 2 Receptor Blocker

avapro

Boxed warning

PrescriptionFDA-sourced

70/100

Avapro (Irbesartan) is an angiotensin 2 receptor blocker used to treat Diabetic Nephropathies, Hypertension, Left Ventricular Dysfunction.

(1 data points)
angiotensin 2 receptor blockerdiabetic nephropathieshypertension

Pharmacy pays

From ~$2.45/30· 3 forms Save up to 70% in class
View details →
#2 of 8 in Angiotensin 2 Receptor Blocker

benicar

Boxed warning

PrescriptionFDA-sourced

70/100

Benicar (Olmesartan Medoxomil) is an angiotensin 2 receptor blocker used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Left Ventricular Dysfunction.

(1 data points)
angiotensin 2 receptor blockerdiabetic nephropathiesheart failure

Pharmacy pays

From ~$1.73/30· 3 forms Save up to 55% in class
View details →
#2 of 8 in Angiotensin 2 Receptor Blocker

valsartan

Boxed warning

PrescriptionFDA-sourced

70/100

Valsartan is an angiotensin 2 receptor blocker used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Left Ventricular Dysfunction.

(11 data points)
angiotensin 2 receptor blockerdiabetic nephropathiesheart failure

Pharmacy pays

From ~$3.00/30· 4 forms Save up to 72% in class
View details →

irbesartan

PrescriptionFDA-sourced

66/100

Irbesartan is an angiotensin 2 receptor blocker used to treat Diabetic Nephropathies, Hypertension, Left Ventricular Dysfunction.

(44 data points)
angiotensin 2 receptor blockerdiabetic nephropathieshypertension

Pharmacy pays

From ~$2.45/30· 3 forms Save up to 70% in class
View details →

arbli

Boxed warning

PrescriptionFDA-sourced

New

Arbli (Losartan Potassium) is an angiotensin 2 receptor blocker used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Left Ventricular Hypertrophy.

angiotensin 2 receptor blockerdiabetic nephropathiesheart failure

Pharmacy pays

From ~$0.64/30· 3 forms
View details →

telmisartan

Boxed warning

PrescriptionFDA-sourced

New

Telmisartan is an angiotensin 2 receptor blocker used to treat Diabetic Nephropathies, Heart Failure, Hypertension, Left Ventricular Dysfunction.

angiotensin 2 receptor blockerdiabetic nephropathiesheart failure

Pharmacy pays

From ~$3.15/30· 3 forms Save up to 78% in class
View details →

Frequently asked

What is the best angiotensin 2 receptor blocker for hypertension?
By our independent recall-safety rating — not an efficacy measure — micardis ranks highest among Angiotensin 2 Receptor Blocker drugs used for hypertension. Always consult a professional.
Which angiotensin 2 receptor blocker drugs treat hypertension?
pharmaranks lists 8 Angiotensin 2 Receptor Blocker products used for hypertension, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.