Best Aldosterone Antagonist for hypertension
Top-rated pick: Eplerenone — pharmaranks score 70/100, the highest of the 4 Aldosterone Antagonist drugs used for hypertension, ranked by our independent FDA recall-safety score. Compare them with all treatments for hypertension or the full Aldosterone Antagonist class. Not medical advice — always consult a professional.
Quick answer: Of the 4 aldosterone antagonist drugs we rate for hypertension, all are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for hypertension; the right choice depends on your situation, so confirm it with your prescriber.
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Top aldosterone antagonist for hypertension: 1. Eplerenone · 2. Carospir · 3. Inspra
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | Generic | $10 | View → | |
| 2 | Not yet rated | Prescription | Suspension | Generic | $3 | View → | |
| 3 | Not yet rated | Prescription | Tablet | Generic | $10 | View → | |
| 4 | Not yet rated | Prescription | Suspension | Generic | $3 | View → |
Full ranking · 4 drugs
eplerenone
PrescriptionFDA-sourced
Eplerenone is an aldosterone antagonist used to treat Hypertension, Systolic Heart Failure.
Pharmacy pays
From ~$9.53/30· 2 forms Save up to 74% in classcarospir
PrescriptionFDA-sourced
Carospir (Spironolactone) is an aldosterone antagonist used to treat Ascites, Edema, Heart Failure, Hirsutism.
Pharmacy pays
From ~$1.34/30· 4 forms
inspra
PrescriptionFDA-sourced
Inspra (Eplerenone) is an aldosterone antagonist used to treat Hypertension, Systolic Heart Failure.
Pharmacy pays
From ~$9.53/30· 2 forms Save up to 74% in classspironolactone
PrescriptionFDA-sourced
Spironolactone is an aldosterone antagonist used to treat Ascites, Edema, Heart Failure, Hirsutism.
Pharmacy pays
From ~$1.34/30· 4 formsFrequently asked
- What is the best aldosterone antagonist for hypertension?
- By our independent recall-safety rating — not an efficacy measure — eplerenone ranks highest among Aldosterone Antagonist drugs used for hypertension. Always consult a professional.
- Which aldosterone antagonist drugs treat hypertension?
- pharmaranks lists 4 Aldosterone Antagonist products used for hypertension, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
Where this ranking comes from
Our score is computed from public FDA data — not from opinion, sponsorship or user votes. How we rate.
- FDA Drug Enforcement (recall) database — the recall history behind the safety score
- DailyMed (NIH National Library of Medicine) — the FDA labels we quote for uses, dosing and warnings
- Drugs@FDA — approvals, strengths and marketing status