Best Alkylating Drug for glioblastoma
Top-rated pick: Gliadel — pharmaranks score 70/100, the highest of the 3 Alkylating Drug drugs used for glioblastoma, ranked by our independent FDA recall-safety score. Compare them with all treatments for glioblastoma or the full Alkylating Drug class. Not medical advice — always consult a professional.
Quick answer: Of the 3 alkylating drug drugs we rate for glioblastoma, 1 is available as lower-cost generics, and most are wafer. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for glioblastoma; the right choice depends on your situation, so confirm it with your prescriber.
How alkylating drug work
Alkylating chemotherapy drugs attach chemical groups to a cell's DNA, forming cross-links that lock the two DNA strands together. This damage stops the cell from copying its DNA and dividing, which triggers it to die; because they are not limited to one phase of the cell cycle, they can act on cells whether or not they are actively dividing.
Top alkylating drug for glioblastoma: 1. Gliadel · 2. Bicnu · 3. Temozolomide
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Wafer | No data | — | View → | |
| 2 | Not yet rated | Prescription | Kit | No data | — | View → | |
| 3 | Not yet rated | Prescription | Capsule | Generic | $149 | View → |
Full ranking · 3 drugs
gliadel
PrescriptionFDA-sourced
Gliadel (Carmustine) is an alkylating drug used to treat Brain Neoplasms, Carcinoma, Colonic Neoplasms, Ependymoma.
Price varies
bicnu
Boxed warningPrescriptionFDA-sourced
Bicnu (Carmustine) is an alkylating drug used to treat Brain Neoplasms, Carcinoma, Colonic Neoplasms, Ependymoma.
Price varies
temozolomide
PrescriptionFDA-sourced
Temozolomide is an alkylating drug used to treat Glioblastoma, Melanoma.
Pharmacy pays
From ~$55.07/30· 6 formsFrequently asked
- What is the best alkylating drug for glioblastoma?
- By our independent recall-safety rating — not an efficacy measure — gliadel ranks highest among Alkylating Drug drugs used for glioblastoma. Always consult a professional.
- Which alkylating drug drugs treat glioblastoma?
- pharmaranks lists 3 Alkylating Drug products used for glioblastoma, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.