Sesame review: what it prescribes, what it costs, who it suits
FDA-approved only. The pick if you want to choose your own clinician and keep everything FDA-approved. You do the mental arithmetic (care fee plus a separately-billed drug), but you are never routed toward a compounded copy.
- What it prescribes
- Branded, FDA-approved drugs only — Sesame's weight-loss page lists Wegovy (pen and pill), Zepbound, Ozempic, Mounjaro and Rybelsus, with no compounded option shown.
- How the consult works
- A video visit with a provider you choose yourself (a rarity here), unlimited messaging, and lab work through Quest in most states.
- Insurance
- Sesame does not bill insurance for the visit or subscription (that part is cash-pay); your own pharmacy insurance can still cover the branded drug, and the weight-loss program's providers can file the prior-authorization paperwork.
- What it costs
- Care is roughly $59–$99/mo (cash-pay); the medication is billed separately at self-pay prices starting around $149/mo and rising with dose. With covered insurance plus a savings card the drug can drop to a low copay. As of mid-2026 — verify current.
What to watch with Sesame
Two separate bills — the subscription and the medication — on possibly different cycles; budget the sum, not the sticker.
Go to Sesame
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Frequently asked questions
Does Sesame prescribe FDA-approved GLP-1s or compounded copies?
FDA-approved only. Branded, FDA-approved drugs only — Sesame's weight-loss page lists Wegovy (pen and pill), Zepbound, Ozempic, Mounjaro and Rybelsus, with no compounded option shown.
How does a Sesame consultation work?
A video visit with a provider you choose yourself (a rarity here), unlimited messaging, and lab work through Quest in most states.
Does Sesame take insurance?
Sesame does not bill insurance for the visit or subscription (that part is cash-pay); your own pharmacy insurance can still cover the branded drug, and the weight-loss program's providers can file the prior-authorization paperwork.
What does Sesame cost?
Care is roughly $59–$99/mo (cash-pay); the medication is billed separately at self-pay prices starting around $149/mo and rising with dose. With covered insurance plus a savings card the drug can drop to a low copay. As of mid-2026 — verify current. Prices in this market move quickly — treat this as the shape of the bill, not a quote.
Is a compounded GLP-1 from any service the same as the branded drug?
No. A compounded product is not FDA-approved: the agency has not reviewed that specific product for identity, potency, purity or sterility. The shortages that made routine compounding lawful ended — tirzepatide October 2, 2024, semaglutide February 21, 2025 — and in 2026 the FDA has been issuing warning letters to telehealth companies over how compounded GLP-1s are marketed. That is the single fact that reorders this market, and it applies whichever service you pick.
Compare with the others
Sources: Sesame — weight-loss medications (branded menu) ↗
We rate medicines, not companies, and we do not give a telehealth service a score — our ratings are built on FDA recall data about drugs, and no equivalent data exists about a business. Prices and programme terms in this market change quickly; verify the current terms on the service’s own site before paying. Not medical advice.