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Best supplements for immune support

The 19 supplements people most often use for immune support. Supplements aren't FDA recall-rated like drugs and the evidence varies, so we list them as options — not a fabricated ranking — and tell you what to look for. Not medical advice.

By the pharmaranks editorial teamReviewed against NIH & NCCIH sourcesHow we research
  1. 1

    Astragalus

    Astragalus Membranaceus

    An adaptogenic root traditionally used for immune and energy support.

    Benefits, dosage & safety →
  2. 2

    Black Seed Oil

    Nigella Sativa

    Oil from black cumin seeds, traditionally used for immune and inflammatory support.

    Benefits, dosage & safety →
  3. 3

    Chaga

    Inonotus Obliquus

    A medicinal mushroom traditionally used for immune and antioxidant support.

    Benefits, dosage & safety →
  4. 4

    Colostrum

    Bovine Colostrum

    Early-milk antibodies taken for immune and gut support.

    Benefits, dosage & safety →
  5. 5

    Cordyceps

    Cordyceps

    A medicinal mushroom traditionally used for energy and stamina.

    Benefits, dosage & safety →
  6. 6

    Echinacea

    Echinacea

    Dosage Adults take 1 tablet three times daily, dissolving on the tongue.

    Benefits, dosage & safety →
  7. 7

    Elderberry

    Sambucus Nigra

    Berry extract popular for immune and seasonal support.

    Benefits, dosage & safety →
  8. 8

    Concentrated garlic (allicin) taken for heart and immune support.

    Benefits, dosage & safety →
  9. 9

    Ginseng

    Panax Ginseng

    An adaptogenic root traditionally used for energy and vitality.

    Benefits, dosage & safety →
  10. 10

    Holy Basil

    Tulsi (Ocimum Sanctum)

    An adaptogenic herb (tulsi) traditionally used for stress and immune support.

    Benefits, dosage & safety →
  11. 11

    An extract rich in oleuropein, taken for immune and cardiovascular support.

    Benefits, dosage & safety →
  12. 12

    Oregano Oil

    Oil of Oregano

    A concentrated herbal oil taken for immune and gut support.

    Benefits, dosage & safety →
  13. 13

    Probiotics

    Lactobacillus & Bifidobacterium

    Live beneficial bacteria supporting digestive and immune health.

    Benefits, dosage & safety →
  14. 14

    Propolis

    Bee Propolis

    A bee-made resin taken for immune and throat support.

    Benefits, dosage & safety →
  15. 15

    Reishi

    Ganoderma Lucidum

    A medicinal mushroom traditionally used for immune support and calm.

    Benefits, dosage & safety →
  16. 16

    Sea Moss

    Irish Moss (Chondrus Crispus)

    A mineral-rich seaweed, popular as a whole-food source of iodine and trace minerals.

    Benefits, dosage & safety →
  17. 17

    Turkey Tail

    Trametes Versicolor

    A medicinal mushroom studied for immune and gut support.

    Benefits, dosage & safety →
  18. 18

    Vitamin A

    Retinol

    A fat-soluble vitamin essential for vision, immunity, and skin.

    Benefits, dosage & safety →

What to look for in a immune support supplement

With supplements, quality varies more by brand than by ingredient. Favor brands with independent third-party testing and certification — NSF, NSF Certified for Sport, USP Verified, Informed Sport — over unverified labels.

FAQ

What is the best supplement for immune support?
There's rarely a single best — the options below are the supplements most commonly used for immune support. Evidence strength varies by ingredient and by person. Favor a form from a brand with independent third-party testing (NSF, USP Verified, Informed Sport), and check with a healthcare professional before starting.
Are immune support supplements FDA-approved?
No. The FDA regulates supplements as food, not drugs — they aren't approved for safety and effectiveness before sale. That makes third-party testing and certification the most useful quality signal, which is what we point to.
Do supplements replace medication for immune support?
No. Supplements are not a substitute for prescribed treatment. This page is general reference, not medical advice — talk to a licensed professional, especially if you take medication.

This page is general reference and not medical advice. Supplement evidence varies and is often limited; statements here have not been evaluated by the FDA. Consult a licensed healthcare professional before starting any supplement.