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clomiPRAMINE Hydrochloride Capsules USP 25 mg recall

FDA recall D-0537-2025 · initiated Jun 27, 2025

By the pharmaranks editorial teamReviewed against the FDA (openFDA) sourcesUpdated Jul 30, 2025How we research

Lupin Pharmaceuticals Inc. recalled clomiPRAMINE Hydrochloride Capsules USP 25 mg in Jun 2025 — an FDA Class II recall (D-0537-2025) because Failed Impurities/Degradation Specifications: an out of specification result observed in degradation product test (any unspecified degradation product) during retention sample testing at expiry.

May cause temporary or medically reversible harm; low probability of serious harm.

Why it was recalled

Failed Impurities/Degradation Specifications: an out of specification result observed in degradation product test (any unspecified degradation product) during retention sample testing at expiry.

An impurity above the accepted limit

A by-product of manufacturing or storage exceeded the limit the FDA accepts. Nitrosamines are the common example: the concern is long-term exposure, not immediate danger from one dose.

This is a manufacturing or quality failure, not a finding that the medicine is unsafe to take — across every recall we hold, none was issued for that reason. It does not mean the batch was harmless.

Is your product affected? Check the lot number

A recall covers only specific lots. Find the lot number and expiration date on your package and compare them to the affected codes below — if yours is not listed, it was not part of this recall.

Lot # M300464, exp. date June, 2025

Quantity recalled: 2,724 bottles

Details

Product
clomiPRAMINE Hydrochloride Capsules USP 25 mg, 100 count bottles, 5801 Pelican Bay Boulevard, Suite 500, Naples, Florida 34108, NDC# 68180-492-01
Recalling company
Lupin Limited
Classification
Class II
Status
Terminated
Type
Voluntary: Firm initiated
Distribution
Nationwide.
Initiated
Jun 27, 2025
FDA report date
Jul 30, 2025
What to do.If you have a recalled product, don't throw away questions — check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This page reproduces public FDA data and is not medical advice.

Frequently asked

Was clomiPRAMINE Hydrochloride Capsules USP 25 mg recalled?
Lupin Pharmaceuticals Inc. recalled clomiPRAMINE Hydrochloride Capsules USP 25 mg in Jun 2025 — an FDA Class II recall (D-0537-2025) because Failed Impurities/Degradation Specifications: an out of specification result observed in degradation product test (any unspecified degradation product) during retention sample testing at expiry. May cause temporary or medically reversible harm; low probability of serious harm.
Why was clomiPRAMINE Hydrochloride Capsules USP 25 mg recalled?
Per the FDA enforcement record, the reason for recall D-0537-2025 was: Failed Impurities/Degradation Specifications: an out of specification result observed in degradation product test (any unspecified degradation product) during retention sample testing at expiry.
Is a recalled clomiPRAMINE Hydrochloride Capsules USP 25 mg dangerous to take?
An FDA recall removes specific lots from the market for a defined reason and does not by itself mean the medicine is unsafe for everyone — your specific lot may never have been affected. May cause temporary or medically reversible harm; low probability of serious harm. Check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This reproduces public FDA data and is not medical advice.
Which lots of clomiPRAMINE Hydrochloride Capsules USP 25 mg are affected?
Distributed: Nationwide.. The recall covers these lots — Lot # M300464, exp. date June, 2025. Check the lot number and expiration date on your package against this list; if yours is not listed, it was not part of recall D-0537-2025.

Source: openFDA Drug Enforcement record D-0537-2025

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