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Carboxymethylcellulose Sodium Ophthalmic Solution 0.5% recall

FDA recall D-0406-2025 · initiated Apr 23, 2025

By the pharmaranks editorial teamReviewed against the FDA (openFDA) sourcesUpdated May 14, 2025How we research

BRS Analytical Services, LLC recalled Carboxymethylcellulose Sodium Ophthalmic Solution 0.5% in Apr 2025 — an FDA Class II recall (D-0406-2025) because cGMP deviations and lack of assurance of sterility.

May cause temporary or medically reversible harm; low probability of serious harm.

Why it was recalled

cGMP deviations and lack of assurance of sterility.

Sterility could not be assured

The maker could not guarantee the product was sterile. That matters most for injections and eye products, where a contaminated dose reaches past the body's defences.

This is a manufacturing or quality failure, not a finding that the medicine is unsafe to take — across every recall we hold, none was issued for that reason. It does not mean the batch was harmless.

Is your product affected? Check the lot number

A recall covers only specific lots. Find the lot number and expiration date on your package and compare them to the affected codes below — if yours is not listed, it was not part of this recall.

Lot, expiry: Lot 103, exp 4/26/25; Lot 104, exp 5/03/25; Lot 108, exp 6/29/25; Lot 109, exp 7/18/25; Lot 110, exp 8/17/25; Lot 111, exp 8/22/25; Lot 112, exp 8/27/25; Lot 113, exp 9/18/25; Lot 125, exp 10/23/25; Lot 130, exp 11/09/25; Lot 131, exp 11/14/25; Lot 132, exp 11/27/25; Lot 133, exp 11/30/25; Lot 134, exp 12/05/25; Lot 135, exp 12/11/25; Lot 136, exp 12/14/25; Lot 137, exp 1/02/26; Lot 139, exp 1/15/26; Lot 140, exp 1/19/26; Lot 141, exp 1/25/26; Lot 151, exp 3/18/26; Lot 152, exp 3/21/26; Lot 153, exp 3/25/26; Lot 154, exp 3/28/26; Lot 155, exp 4/01/26; Lot 156, exp 4/08/26; Lot 157, exp 4/11/26; Lot 160, exp 4/26/26; Lot 180, exp 8/08/26; Lot 181, exp 8/12/26; Lot 182, exp 8/18/26; Lot 183, exp 8/21/26; Lot 184, exp 8/26/26; Lot 185, exp 9/04/26; Lot 186, exp 9/09/26; Lot 187, exp 9/16/26; Lot 188, exp 9/18/26; Lot 189, exp 9/21/26; Lot 190, exp 9/25/26; Lot 191, exp 9/28/26; Lot 192, exp 10/02/26; Lot 208, exp 12/11/26; Lot 209, exp 12/16/26; Lot 212, exp 1/15/27; Lot 213, exp 1/21/27; Lot 214, exp 1/24/27; Lot 215, exp 2/02/27; Lot 216, exp 2/04/27; Lot 224, exp 3/27/27.

Quantity recalled: 32,876 cases (24 cartons per case)

Details

Product
Carboxymethylcellulose Sodium Ophthalmic Solution 0.5%, Carboxymethlycellulose Sodium 0.5% Eye Lubricant, Lubricating Eye Drops, Moisturizing, Sterile, 0.5 FL OZ (15mL) per dropper bottle, Distributed by: AvKARE, Pulaski, TN 38478, NDC: 50268-068-15.
Recalling company
BRS Analytical Services, LLC
Classification
Class II
Status
Ongoing
Type
Voluntary: Firm initiated
Distribution
Nationwide in the USA
Initiated
Apr 23, 2025
FDA report date
May 14, 2025
What to do.If you have a recalled product, don't throw away questions — check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This page reproduces public FDA data and is not medical advice.

Frequently asked

Was Carboxymethylcellulose Sodium Ophthalmic Solution 0.5% recalled?
BRS Analytical Services, LLC recalled Carboxymethylcellulose Sodium Ophthalmic Solution 0.5% in Apr 2025 — an FDA Class II recall (D-0406-2025) because cGMP deviations and lack of assurance of sterility. May cause temporary or medically reversible harm; low probability of serious harm.
Why was Carboxymethylcellulose Sodium Ophthalmic Solution 0.5% recalled?
Per the FDA enforcement record, the reason for recall D-0406-2025 was: cGMP deviations and lack of assurance of sterility.
Is a recalled Carboxymethylcellulose Sodium Ophthalmic Solution 0.5% dangerous to take?
An FDA recall removes specific lots from the market for a defined reason and does not by itself mean the medicine is unsafe for everyone — your specific lot may never have been affected. May cause temporary or medically reversible harm; low probability of serious harm. Check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This reproduces public FDA data and is not medical advice.
Which lots of Carboxymethylcellulose Sodium Ophthalmic Solution 0.5% are affected?
Distributed: Nationwide in the USA. The recall covers these lots — Lot, expiry: Lot 103, exp 4/26/25; Lot 104, exp 5/03/25; Lot 108, exp 6/29/25; Lot 109, exp 7/18/25; Lot 110, exp 8/17/25; Lot 111, exp 8/22/25; Lot 112, exp 8/27/25; Lot 113, exp 9/18/25; Lot 125, exp 10/23/25; Lot 130, exp 11/09/25; Lot 131, exp 11/14/25; Lot 132, exp 11/27/25; Lot 133, exp 11/30/25; Lot 134, exp 12/…. Check the lot number and expiration date on your package against this list; if yours is not listed, it was not part of recall D-0406-2025.

Source: openFDA Drug Enforcement record D-0406-2025

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