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chlorproMAZINE Hydrochloride Tablets recall

FDA recall D-0361-2025 · initiated Apr 3, 2025

By the pharmaranks editorial teamReviewed against the FDA (openFDA) sourcesUpdated Apr 16, 2025How we research

Zydus Pharmaceuticals (USA) Inc recalled chlorproMAZINE Hydrochloride Tablets in Apr 2025 — an FDA Class II recall (D-0361-2025) because CGMP deviations: presence of N-Nitroso-Desmethyl Chlorpromazine impurity above the recommended interim limit.

May cause temporary or medically reversible harm; low probability of serious harm.

Why it was recalled

CGMP deviations: presence of N-Nitroso-Desmethyl Chlorpromazine impurity above the recommended interim limit

An impurity above the accepted limit

A by-product of manufacturing or storage exceeded the limit the FDA accepts. Nitrosamines are the common example: the concern is long-term exposure, not immediate danger from one dose.

This is a manufacturing or quality failure, not a finding that the medicine is unsafe to take — across every recall we hold, none was issued for that reason. It does not mean the batch was harmless.

Is your product affected? Check the lot number

A recall covers only specific lots. Find the lot number and expiration date on your package and compare them to the affected codes below — if yours is not listed, it was not part of this recall.

Lot #: Z400069, Exp.: 12/31/2025

Quantity recalled: 3144 bottles, pack size: 100's Count

Details

Product
chlorproMAZINE Hydrochloride Tablets, USP 10 mg, Rx Only, 100 Tablets bottles, Manufactured by: Zydus Lifesciences Ltd., Baddi, India, Distributed by: Zydus Pharmaceuticals (USA) Inc., Pennington, NJ 08534, NDC 70710-1129-1
Recalling company
Zydus Pharms
Classification
Class II
Status
Ongoing
Type
Voluntary: Firm initiated
Distribution
Nationwide within U.S - MS, AL, TN, VT, OH, ND, MN, WI, SC, AR, FL, IN, LA, NJ, AZ, TX, KY and PA
Initiated
Apr 3, 2025
FDA report date
Apr 16, 2025
What to do.If you have a recalled product, don't throw away questions — check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This page reproduces public FDA data and is not medical advice.

Frequently asked

Was chlorproMAZINE Hydrochloride Tablets recalled?
Zydus Pharmaceuticals (USA) Inc recalled chlorproMAZINE Hydrochloride Tablets in Apr 2025 — an FDA Class II recall (D-0361-2025) because CGMP deviations: presence of N-Nitroso-Desmethyl Chlorpromazine impurity above the recommended interim limit. May cause temporary or medically reversible harm; low probability of serious harm.
Why was chlorproMAZINE Hydrochloride Tablets recalled?
Per the FDA enforcement record, the reason for recall D-0361-2025 was: CGMP deviations: presence of N-Nitroso-Desmethyl Chlorpromazine impurity above the recommended interim limit
Is a recalled chlorproMAZINE Hydrochloride Tablets dangerous to take?
An FDA recall removes specific lots from the market for a defined reason and does not by itself mean the medicine is unsafe for everyone — your specific lot may never have been affected. May cause temporary or medically reversible harm; low probability of serious harm. Check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This reproduces public FDA data and is not medical advice.
Which lots of chlorproMAZINE Hydrochloride Tablets are affected?
Distributed: Nationwide within U.S - MS, AL, TN, VT, OH, ND, MN, WI, SC, AR, FL, IN, LA, NJ, AZ, TX, KY and PA. The recall covers these lots — Lot #: Z400069, Exp.: 12/31/2025. Check the lot number and expiration date on your package against this list; if yours is not listed, it was not part of recall D-0361-2025.

Source: openFDA Drug Enforcement record D-0361-2025

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