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Class IOngoing

Prograf (tacrolimus) capsules recall

FDA recall D-0211-2025 · initiated Dec 23, 2024

By the pharmaranks editorial teamReviewed against the FDA (openFDA) sourcesUpdated Feb 5, 2025How we research

Astellas Pharma US Inc. recalled Prograf (tacrolimus) capsules in Dec 2024 — an FDA Class I recall (D-0211-2025) because Failed Tablet/Capsule Specifications: Bottles shipped to the USA may contain empty capsules.

Most serious — a reasonable probability that use will cause serious harm or death.

Why it was recalled

Failed Tablet/Capsule Specifications: Bottles shipped to the USA may contain empty capsules

The manufacturing process itself

The FDA found the process itself out of compliance, usually before any defective product was identified.

This is a manufacturing or quality failure, not a finding that the medicine is unsafe to take — across every recall we hold, none was issued for that reason. It does not mean the batch was harmless.

Is your product affected? Check the lot number

A recall covers only specific lots. Find the lot number and expiration date on your package and compare them to the affected codes below — if yours is not listed, it was not part of this recall.

Lot# 0E3353D, Exp 03/31/2026

Quantity recalled: 14,340 100-count bottles

Details

Product
Prograf (tacrolimus) capsules, USP, 0.5 mg, 100-count bottle, Rx Only, Product of Japan, Distributed by: Astellas Pharma US, Inc., Northbrook, IL 60062, NDC 0469-0607-73.
Recalling company
Astellas
Classification
Class I
Status
Ongoing
Type
Voluntary: Firm initiated
Distribution
Nationwide in the USA
Initiated
Dec 23, 2024
FDA report date
Feb 5, 2025
What to do.If you have a recalled product, don't throw away questions — check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This page reproduces public FDA data and is not medical advice.

Frequently asked

Was Prograf (tacrolimus) capsules recalled?
Astellas Pharma US Inc. recalled Prograf (tacrolimus) capsules in Dec 2024 — an FDA Class I recall (D-0211-2025) because Failed Tablet/Capsule Specifications: Bottles shipped to the USA may contain empty capsules. Most serious — a reasonable probability that use will cause serious harm or death.
Why was Prograf (tacrolimus) capsules recalled?
Per the FDA enforcement record, the reason for recall D-0211-2025 was: Failed Tablet/Capsule Specifications: Bottles shipped to the USA may contain empty capsules
Is a recalled Prograf (tacrolimus) capsules dangerous to take?
An FDA recall removes specific lots from the market for a defined reason and does not by itself mean the medicine is unsafe for everyone — your specific lot may never have been affected. Most serious — a reasonable probability that use will cause serious harm or death. Check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This reproduces public FDA data and is not medical advice.
Which lots of Prograf (tacrolimus) capsules are affected?
Distributed: Nationwide in the USA. The recall covers these lots — Lot# 0E3353D, Exp 03/31/2026. Check the lot number and expiration date on your package against this list; if yours is not listed, it was not part of recall D-0211-2025.

Source: openFDA Drug Enforcement record D-0211-2025

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