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Guaifenesin Dextromethorphan Syrup recall

FDA recall D-0049-2025 · initiated Nov 7, 2024

By the pharmaranks editorial teamReviewed against the FDA (openFDA) sourcesUpdated Nov 27, 2024How we research

The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories recalled Guaifenesin Dextromethorphan Syrup in Nov 2024 — an FDA Class II recall (D-0049-2025) because Failed Impurity/Degradation Specifications.

May cause temporary or medically reversible harm; low probability of serious harm.

Why it was recalled

Failed Impurity/Degradation Specifications

An impurity above the accepted limit

A by-product of manufacturing or storage exceeded the limit the FDA accepts. Nitrosamines are the common example: the concern is long-term exposure, not immediate danger from one dose.

This is a manufacturing or quality failure, not a finding that the medicine is unsafe to take — across every recall we hold, none was issued for that reason. It does not mean the batch was harmless.

Is your product affected? Check the lot number

A recall covers only specific lots. Find the lot number and expiration date on your package and compare them to the affected codes below — if yours is not listed, it was not part of this recall.

Lot #: C00128, Exp. Date 04/2025; C00146, Exp.Date 07/2025

Quantity recalled: N/A

Details

Product
Guaifenesin Dextromethorphan Syrup, 200 mg/20mg per 10 mL, Major Pharmaceuticals 8401 Bearing Drive, Suite 100, Indianapolis, IN, 46268, NDC 0904-7135-72
Recalling company
The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories
Classification
Class II
Status
Terminated
Type
Voluntary: Firm initiated
Distribution
Nationwide within the United States
Initiated
Nov 7, 2024
FDA report date
Nov 27, 2024
What to do.If you have a recalled product, don't throw away questions — check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This page reproduces public FDA data and is not medical advice.

Frequently asked

Was Guaifenesin Dextromethorphan Syrup recalled?
The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories recalled Guaifenesin Dextromethorphan Syrup in Nov 2024 — an FDA Class II recall (D-0049-2025) because Failed Impurity/Degradation Specifications. May cause temporary or medically reversible harm; low probability of serious harm.
Why was Guaifenesin Dextromethorphan Syrup recalled?
Per the FDA enforcement record, the reason for recall D-0049-2025 was: Failed Impurity/Degradation Specifications
Is a recalled Guaifenesin Dextromethorphan Syrup dangerous to take?
An FDA recall removes specific lots from the market for a defined reason and does not by itself mean the medicine is unsafe for everyone — your specific lot may never have been affected. May cause temporary or medically reversible harm; low probability of serious harm. Check the FDA notice for the affected lot numbers and expiration dates, and ask your pharmacist or doctor before stopping a prescribed medicine. This reproduces public FDA data and is not medical advice.
Which lots of Guaifenesin Dextromethorphan Syrup are affected?
Distributed: Nationwide within the United States. The recall covers these lots — Lot #: C00128, Exp. Date 04/2025; C00146, Exp.Date 07/2025. Check the lot number and expiration date on your package against this list; if yours is not listed, it was not part of recall D-0049-2025.

Source: openFDA Drug Enforcement record D-0049-2025

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