Skip to content
ppharmaranks
Menu

zegerid otc

Zegerid OTC is a combination medicine containing Omeprazole and Sodium Bicarbonate.

Omeprazole and Sodium Bicarbonate · by Riley Consumer

Available as a generic: Omeprazole and Sodium Bicarbonate

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
~$1.52 /30
Check price on AmazonWe may earn a commission · never affects ratings

Key facts

Active ingredient
Omeprazole and Sodium Bicarbonate
Form
Capsule
Strength
Omeprazole 20MG; Sodium Bicarbonate 1.1GM
Type
Over-the-counter (OTC)
Brand or generic
Brand-name
Manufacturer
Riley Consumer
Half-life
about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults (how long it stays in your system)
What the pharmacy pays
~$1.52 for 30 — not your price
FDA application
NDA022281

What is Zegerid OTC?

From the FDA label:Use treats frequent heartburn (occurs 2 or more days a week) not intended for immediate relief of heartburn. This drug may take 1 to 4 days for full effect.

How to use

Directions for adults 18 years of age and older this product is to be used once a day (every 24 hours), every day for 14 days it may take 1 to 4 days for full effect, although some people get complete relief of symptoms within 24 hours 14-Day Course of Treatment swallow 1 capsule with a glass of water at least 1 hour before eating in the morning take every day for 14 days do not take more than 1 capsule a day do not chew or crush the capsule do not open capsule and sprinkle on food do not use for more than 14 days unless directed by your doctor Repeated 14-day Courses (if needed) you may repeat a 14-day course every 4 months do not take for more than 14 days or more often than every 4 months unless directed by a doctor children under 18 years of age: ask a doctor Heartburn in children may sometimes be caused by a serious condition.

Warnings

Important safety information

Allergy alert: do not use if you are allergic to omeprazole. omeprazole may cause severe skin reactions Symptoms may include: skin reddening blisters rash If an allergic reaction occurs, stop use and seek medical help right away

How long does Omeprazole and Sodium Bicarbonate stay in your body?

The elimination half-life of omeprazole and sodium bicarbonate is about 0.5 to 1 hour (roughly half an hour to an hour) in healthy adults — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The half-life is longer in older adults (about 1 hour) and in people with chronic liver disease (nearly 3 hours); its metabolites have little or no activity, but because omeprazole irreversibly binds the stomach's acid pump, its acid-blocking effect lasts far longer than this short half-life would suggest.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: OMEPRAZOLE capsule, delayed release — DailyMed (FDA label), Clinical Pharmacology / Pharmacokinetics.

Dosage forms

Capsule

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How much does Zegerid OTC cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.52 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Zegerid OTC?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Zegerid OTC. To pay less, look for a store-brand version with the same active ingredient (Omeprazole and Sodium Bicarbonate), which is typically cheaper, and compare unit prices. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Zegerid OTC?
Zegerid OTC is marketed by Riley Consumer. You can see Riley Consumer's full profile, rating, and other products on pharmaranks.
Is Zegerid OTC a brand-name or generic drug?
Zegerid OTC is a brand-name product with the active ingredient Omeprazole and Sodium Bicarbonate. Lower-cost generic equivalents containing Omeprazole and Sodium Bicarbonate are available — ask your pharmacist.
Is Zegerid OTC available over the counter?
Yes. Zegerid OTC is an over-the-counter (OTC) product — you can buy it without a prescription. Follow the label directions and ask a pharmacist if you're unsure whether it's right for you.
What forms does Zegerid OTC come in?
Zegerid OTC is currently marketed as capsule, per the FDA's National Drug Code Directory.
Is Zegerid OTC FDA-registered?
Zegerid OTC is on record with the U.S. FDA under application number NDA022281. You can verify this on its official FDA label.
Is Zegerid OTC safe?
There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Zegerid OTC. Review its FDA-label side effects and warnings below, and always consult a licensed professional.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

Reviews

No reviews yet. Be the first to write one.

Write a review

Reviews are user opinions, not medical advice. Consult a licensed professional.

People also viewed

Compare Zegerid OTC head-to-head

Guides for this medication

Identify a pill by its imprint →Check a drug interaction →Drug recalls →

Browse medications A–Z

Research products from A to Z, compare independent ratings, and find alternatives.