What does Zefazone treat?

Zefazone (Cefmetazole Sodium) may be used to treat bacterial infections, escherichia coli infections, klebsiella infections, proteus infections, serratia infections, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

Is there a coupon or discount for Zefazone?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Zefazone. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Zefazone is marketed by Pharmacia and Upjohn. You can see Pharmacia and Upjohn's full profile, rating, and other products on pharmaranks.

Is Zefazone a brand-name or generic drug?

Zefazone is a brand-name product with the active ingredient Cefmetazole Sodium.

Is Zefazone available over the counter?

No. Zefazone is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Zefazone come in?

Zefazone is currently marketed as injectable, per the FDA's National Drug Code Directory.

Is Zefazone FDA-registered?

Zefazone is on record with the U.S. FDA under application number NDA050637. You can verify this on its official FDA label.

zefazone

Zefazone (Cefmetazole Sodium) is a medication used to treat Bacterial Infections, Escherichia Coli Infections, Klebsiella Infections, Proteus Infections.

Cefmetazole Sodium · by Pharmacia and Upjohn

Not yet rated· sourced from the FDA label

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Verified againstopenFDANIH DailyMedRxClass

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Key facts

Active ingredient: Cefmetazole Sodium
Form: Injectable
Strength: Cefmetazole Sodium EQ 1GM BASE/VIAL **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Cefmetazole Sodium EQ 2GM BASE/VIAL **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type: Prescription (Rx)
Brand or generic: Brand-name
May treat: bacterial infections, escherichia coli infections, klebsiella infections
Manufacturer: Pharmacia and Upjohn
FDA application: NDA050637
Availability: Discontinued (per FDA)

May treat (source: NIH RxClass)

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Zefazone treat?: Zefazone (Cefmetazole Sodium) may be used to treat bacterial infections, escherichia coli infections, klebsiella infections, proteus infections, serratia infections, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
Is there a coupon or discount for Zefazone?: pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Zefazone. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Zefazone?: Zefazone is marketed by Pharmacia and Upjohn. You can see Pharmacia and Upjohn's full profile, rating, and other products on pharmaranks.
Is Zefazone a brand-name or generic drug?: Zefazone is a brand-name product with the active ingredient Cefmetazole Sodium.
Is Zefazone available over the counter?: No. Zefazone is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Zefazone come in?: Zefazone is currently marketed as injectable, per the FDA's National Drug Code Directory.
Is Zefazone FDA-registered?: Zefazone is on record with the U.S. FDA under application number NDA050637. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about CEFMETAZOLE SODIUM

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 403 reports naming CEFMETAZOLE SODIUM — the active ingredient in Zefazone, and the FDA flagged 98% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

pyrexia36 reports
anaemia26 reports
pneumonia21 reports
diarrhoea19 reports
vomiting17 reports
rash16 reports
hepatic function abnormal14 reports
pruritus14 reports

Read these as a signal, not a rate. A report does not mean CEFMETAZOLE SODIUM caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.