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valsartan and hydrochlorothiazide

Valsartan and Hydrochlorothiazide is a combination medicine containing Hydrochlorothiazide and Valsartan.

Hydrochlorothiazide and Valsartan · by Watson Labs Teva

Generic of Diovan Hct

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Hydrochlorothiazide and Valsartan
Form
Tablet
Strength
Hydrochlorothiazide 12.5MG; Valsartan 160MG · Hydrochlorothiazide 12.5MG; Valsartan 320MG · Hydrochlorothiazide 12.5MG; Valsartan 80MG · Hydrochlorothiazide 25MG; Valsartan 160MG · Hydrochlorothiazide 25MG; Valsartan 320MG
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Watson Labs Teva
Half-life
about 6 to 15 hours (the label reports a range, not a single number) (how long it stays in your system)
What the pharmacy pays
~$0.91 for 30 — not your price
FDA application
ANDA091519
Availability
Discontinued (per FDA)

How long does Hydrochlorothiazide and Valsartan stay in your body?

The elimination half-life of hydrochlorothiazide and valsartan is about 6 to 15 hours (the label reports a range, not a single number) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma ELIMINATION half-life. Plasma levels fall bi-exponentially: other FDA labels for hydrochlorothiazide combination products describe a distribution phase of roughly 2 hours before the ~10-hour (6-15 h) elimination phase — the elimination figure is the one given here. Hydrochlorothiazide is NOT a prodrug and is NOT metabolized, so there is no active metabolite that outlasts the parent; more than 95% of the absorbed dose is excreted unchanged in urine. Kidney impairment: the label states plainly that in patients with renal disease plasma concentrations are increased and the elimination half-life is PROLONGED — it does not quantify by how much. The label does not state a different half-life for older adults or for liver impairment, so no number should be assumed for those groups. Absorption (not elimination) is reduced in congestive heart failure. This is a pharmacokinetic figure about how long the drug stays in plasma; it is not a drug-test detection window and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — HYDROCHLOROTHIAZIDE capsule, Clinical Pharmacology (Pharmacokinetics and Metabolism).

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How much does Valsartan and Hydrochlorothiazide cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.91 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Valsartan and Hydrochlorothiazide?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Valsartan and Hydrochlorothiazide. To pay less, Valsartan and Hydrochlorothiazide is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Valsartan and Hydrochlorothiazide?
Valsartan and Hydrochlorothiazide is marketed by Watson Labs Teva. You can see Watson Labs Teva's full profile, rating, and other products on pharmaranks.
Is Valsartan and Hydrochlorothiazide a brand-name or generic drug?
Valsartan and Hydrochlorothiazide is a generic medication; its active ingredient is Hydrochlorothiazide and Valsartan. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Valsartan and Hydrochlorothiazide available over the counter?
No. Valsartan and Hydrochlorothiazide is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Valsartan and Hydrochlorothiazide come in?
Valsartan and Hydrochlorothiazide is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Valsartan and Hydrochlorothiazide FDA-registered?
Valsartan and Hydrochlorothiazide is on record with the U.S. FDA under application number ANDA091519. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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