tolinase
Tolinase (Tolazamide) is a medication used to treat Type 2 Diabetes Mellitus.
Tolazamide · by Pharmacia and Upjohn
Available as a generic: Tolazamide
Key facts
- Active ingredient
- Tolazamide
- Form
- Tablet
- Strength
- Tolazamide 100MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Tolazamide 250MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Tolazamide 500MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- type 2 diabetes mellitus
- Manufacturer
- Pharmacia and Upjohn
- FDA application
- NDA015500
- Availability
- Discontinued (per FDA)
May treat (source: NIH RxClass)
Dosage forms
Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Tolinase treat?
- Tolinase (Tolazamide) may be used to treat type 2 diabetes mellitus, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- Is there a coupon or discount for Tolinase?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Tolinase. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Tolinase?
- Tolinase is marketed by Pharmacia and Upjohn. You can see Pharmacia and Upjohn's full profile, rating, and other products on pharmaranks.
- Is Tolinase a brand-name or generic drug?
- Tolinase is a brand-name product with the active ingredient Tolazamide. Lower-cost generic equivalents containing Tolazamide are available — ask your pharmacist.
- Is Tolinase available over the counter?
- No. Tolinase is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Tolinase come in?
- Tolinase is currently marketed as tablet, per the FDA's National Drug Code Directory.
- Is Tolinase FDA-registered?
- Tolinase is on record with the U.S. FDA under application number NDA015500. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about TOLAZAMIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 74 reports naming TOLAZAMIDE — the active ingredient in Tolinase, and the FDA flagged 72% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- blood glucose increased9 reports
- dyspnoea7 reports
- myocardial infarction6 reports
- fatigue5 reports
- renal failure5 reports
- syncope5 reports
- vomiting5 reports
- chest pain4 reports
Read these as a signal, not a rate. A report does not mean TOLAZAMIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 26, 2026.
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