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tis-u-sol

Tis-U-Sol is a combination medicine containing Magnesium Sulfate, Potassium Chloride, Potassium Phosphate, Monobasic, Sodium Chloride, and Sodium Phosphate.

Magnesium Sulfate and Potassium Chloride and Potassium Phosphate, Monobasic and Sodium Chloride and Sodium Phosphate · by Baxter Hlthcare

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Magnesium Sulfate and Potassium Chloride and Potassium Phosphate, Monobasic and Sodium Chloride and Sodium Phosphate
Form
Irrigant
Strength
Magnesium Sulfate 20MG/100ML; Potassium Chloride 40MG/100ML; Potassium PHOSPHATE, Monobasic 6.25MG/100ML; Sodium Chloride 800MG/100ML; Sodium Phosphate 8.75MG/100ML
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Baxter Hlthcare
What the pharmacy pays
~$0.01 per ml — not your price
FDA application
NDA018508

What is Tis-U-Sol?

From the FDA label:Tis-U-Sol ® Solution (Pentalyte Irrigation) Each 100 mL contains: 800 mg Sodium Chloride, USP, 40 mg Potassium Chloride, USP, 20 mg Magnesium Sulfate, Heptahydrate, USP, 8.75 mg Dibasic Sodium Phosphate, Heptahydrate, USP, 6.25 mg Monobasic Potassium Phosphate, NF. No antimicrobial agent has been added. pH 6.5 (4.0 to 7.0). Osmolarity 288 mOsmol/L (calc.). Sterile, nonpyrogenic. Pour Bottle.

How to use

As directed by a physician. Cautions: Warm in oven to not more than 50°C for a maximum of 60 days. Discard after 60 days of warming. Do not use unless solution is clear and seal is intact. Discard unused portion. Rx only.

Dosage forms

Irrigant

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How much does Tis-U-Sol cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.01 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Tis-U-Sol?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Tis-U-Sol. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Tis-U-Sol?
Tis-U-Sol is marketed by Baxter Hlthcare. You can see Baxter Hlthcare's full profile, rating, and other products on pharmaranks.
Is Tis-U-Sol a brand-name or generic drug?
Tis-U-Sol is a brand-name product with the active ingredient Magnesium Sulfate and Potassium Chloride and Potassium Phosphate, Monobasic and Sodium Chloride and Sodium Phosphate.
Is Tis-U-Sol available over the counter?
No. Tis-U-Sol is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Tis-U-Sol come in?
Tis-U-Sol is currently marketed as irrigant, per the FDA's National Drug Code Directory.
Is Tis-U-Sol FDA-registered?
Tis-U-Sol is on record with the U.S. FDA under application number NDA018508. You can verify this on its official FDA label.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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