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tekturna hct

Tekturna Hct is a combination medicine containing Aliskiren Hemifumarate and Hydrochlorothiazide.

Aliskiren Hemifumarate and Hydrochlorothiazide · by Noden Pharma

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Aliskiren Hemifumarate and Hydrochlorothiazide
Form
Tablet
Strength
Aliskiren Hemifumarate EQ 150MG Base; Hydrochlorothiazide 12.5MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Aliskiren Hemifumarate EQ 150MG Base; Hydrochlorothiazide 25MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Aliskiren Hemifumarate EQ 300MG Base; Hydrochlorothiazide 12.5MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Aliskiren Hemifumarate EQ 300MG Base; Hydrochlorothiazide 25MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Noden Pharma
Half-life
about 6 to 15 hours (the label reports a range, not a single number) (how long it stays in your system)
FDA application
NDA022107
Availability
Discontinued (per FDA)

How long does Aliskiren Hemifumarate and Hydrochlorothiazide stay in your body?

The elimination half-life of aliskiren hemifumarate and hydrochlorothiazide is about 6 to 15 hours (the label reports a range, not a single number) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma ELIMINATION half-life. Plasma levels fall bi-exponentially: other FDA labels for hydrochlorothiazide combination products describe a distribution phase of roughly 2 hours before the ~10-hour (6-15 h) elimination phase — the elimination figure is the one given here. Hydrochlorothiazide is NOT a prodrug and is NOT metabolized, so there is no active metabolite that outlasts the parent; more than 95% of the absorbed dose is excreted unchanged in urine. Kidney impairment: the label states plainly that in patients with renal disease plasma concentrations are increased and the elimination half-life is PROLONGED — it does not quantify by how much. The label does not state a different half-life for older adults or for liver impairment, so no number should be assumed for those groups. Absorption (not elimination) is reduced in congestive heart failure. This is a pharmacokinetic figure about how long the drug stays in plasma; it is not a drug-test detection window and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — HYDROCHLOROTHIAZIDE capsule, Clinical Pharmacology (Pharmacokinetics and Metabolism).

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

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Frequently asked questions

Is there a coupon or discount for Tekturna Hct?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Tekturna Hct. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Tekturna Hct?
Tekturna Hct is marketed by Noden Pharma. You can see Noden Pharma's full profile, rating, and other products on pharmaranks.
Is Tekturna Hct a brand-name or generic drug?
Tekturna Hct is a brand-name product with the active ingredient Aliskiren Hemifumarate and Hydrochlorothiazide.
Is Tekturna Hct available over the counter?
No. Tekturna Hct is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Tekturna Hct come in?
Tekturna Hct is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Tekturna Hct FDA-registered?
Tekturna Hct is on record with the U.S. FDA under application number NDA022107. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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